Modeling pulse wave velocity trajectories-challenges, opportunities, and pitfalls.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 35190033.
- Also identified by DOI 10.1016/j.kint.2021.12.025.
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Abstract
In this commentary, we discuss the analysis of trajectories of pulse wave velocity in a longitudinal cohort study of children with chronic kidney disease (the Cardiovascular Comorbidity in Children with Chronic Kidney Disease - Transplantation study). We revisit the analysis made by the study authors and unravel some additional limitations. We also reevaluate the implicit assumptions that were made in the chosen analysis and suggest extensions of the basic linear mixed model to obtain more differentiated answers to research questions in nephrology.
Medical subject headings
- Pulse Wave Analysis
- Renal Insufficiency, Chronic