What is the Optimal Low-Density Lipoprotein Cholesterol?
Where this comes from
- Record sourced from PubMed, PMID 35227431.
- Also identified by DOI 10.1016/j.mcna.2021.11.005.
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Abstract
One's total atherosclerotic plaque burden is related to his or her cumulative exposure to low-density lipoprotein cholesterol (LDL-C) and other apoB-containing lipoproteins. Long-term exposure to lower LDL-C levels is associated with a lower risk of cardiovascular events compared with shorter term exposure to lower LDL-C. New lipid-reducing agents have been able to reduce LDL-C to previously unseen levels, showing efficacy in safely decreasing rates of atherosclerotic cardiovascular disease in primary and secondary prevention populations. To date, an LDL-C level less than which there is no clinical benefit has not yet been identified.
Medical subject headings
- Atherosclerosis
- Cardiovascular Diseases