Human 8-cell-like cells discovered.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35245463.
- Also identified by DOI 10.1016/j.stem.2022.01.015.
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Abstract
Human naive pluripotent stem cells have the remarkable ability to generate blastoids comprising trophectoderm, epiblast, and hypoblast-like cells. In this issue, Taubenschmid-Stowers et al. (2022) show that human naive pluripotent stem cell cultures contain cells that resemble the 8-cell human embryo, providing a model to study zygotic genome activation.
Medical subject headings
- Germ Layers
- Pluripotent Stem Cells