Mapping the long road to cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35263624.
- Also identified by DOI 10.1016/j.cell.2022.02.020.
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Abstract
Every cell in our body accumulates mutations throughout life, and sometimes an unfortunate combination of mutations drives the initiation of cancer. A new study infers extraordinarily detailed timelines of pre-cancerous evolution by sequencing single-cell genomes in patients with blood malignancies-finding that key mutations can arrive decades before diagnosis.
Medical subject headings
- Neoplasms