NewWave: a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA-seq data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35266509.
- Also identified by DOI 10.1093/bioinformatics/btac149 and PMC identifier 9048694.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We present NewWave, a scalable R/Bioconductor package for the dimensionality reduction and batch effect removal of single-cell RNA sequencing data. To achieve scalability, NewWave uses mini-batch optimization and can work with out-of-memory data, enabling users to analyze datasets with millions of cells. NewWave is implemented as an open-source R package available through the Bioconductor project at https://bioconductor.org/packages/NewWave/. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software