Existence of immunological memory response in true sero-negative individuals post COVID-19 molecular diagnosis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 35271690.
- Also identified by DOI 10.1093/cid/ciac196.
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Abstract
Approximately 1-8% of individuals do not develop antibodies following SARS-CoV-2 infection (sero-negatives). One BNT162b2 dose resulted in potent humoral response in 14 sero-negatives and 15 sero-positives, significantly higher than the response of 15 naïve-individuals, to two doses suggesting that COVID-19 provoked a memory response in individuals without detectable antibodies.