CellWalkR: an R package for integrating and visualizing single-cell and bulk data to resolve regulatory elements.
basic_science · Level V
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- Record sourced from PubMed, PMID 35274675.
- Also identified by DOI 10.1093/bioinformatics/btac150 and PMC identifier 9048661.
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Abstract
CellWalkR is an R package that integrates single-cell open chromatin data with cell type labels and bulk epigenetic data to identify cell type-specific regulatory regions. A Graphics Processing Unit (GPU) implementation and downsampling strategies enable thousands of cells to be processed in seconds. CellWalkR's user-friendly interface provides interactive analysis and visualization of cell labels and regulatory region mappings. CellWalkR is freely available as an R package under a GNU GPL-2.0 License and can be accessed from https://github.com/PFPrzytycki/CellWalkR with an accompanying vignette. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software
- Regulatory Sequences, Nucleic Acid