Intussusception and COVID-19 in Infants: Evidence for an Etiopathologic Correlation.

Scottoni, Federico; Giobbe, Giovanni Giuseppe; Zambaiti, Elisa; Khalaf, Sahira; Sebire, Neil J; Curry, Joe; De Coppi, Paolo; Gennari, Fabrizio · Pediatrics · 2022

case_report · Level V

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Abstract

Nonrespiratory conditions related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been largely described. Ileocolic intussusception has been reported in association with SARS-CoV-2 infection in 10 children, raising the possibility of an etiopathologic role for the virus, but none of these cases documented tissue pathology that would have supported SARS-CoV-2 intestinal inflammation. We report 2 cases of intussusception in patients with SARS-CoV-2 infection who were treated at different pediatric tertiary centers in Europe and provide evidence of the presence of the virus in mesenteric and intestinal tissues of the patients.

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