Avoiding kidney damage in ICU sedation with sevoflurane: use isoflurane instead.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 35331541.
- Also identified by DOI 10.1016/j.bja.2022.02.031.
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Abstract
Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.
Medical subject headings
- Anesthetics, Inhalation
- Isoflurane
- Methyl Ethers