Thyroid Nodules in Children With Familial Adenomatous Polyposis.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 35333786.
- Also identified by DOI 10.14309/ajg.0000000000001747.
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Abstract
Ultrasound screening for thyroid cancer is recommended in familial adenomatous polyposis (FAP). This study investigated the prevalence of thyroid neoplasia in children with FAP. Cross-sectional study of children with FAP at an academic hospital. Clinical and ultrasound data were analyzed for the prevalence of thyroid nodules and cancer. Of 37 children with FAP, 8 (22%) had thyroid nodules and 2 (5%) had thyroid cancer. Nodules (30%) and cancer (9%) were more common among female subjects and rare among male subjects. Thyroid ultrasound screening in adolescence may benefit female subjects with FAP but has limited utility in male subjects.
Medical subject headings
- Adenomatous Polyposis Coli
- Thyroid Neoplasms
- Thyroid Nodule