Characteristics of Diabetic Foot Ulcer Patients Pre- and During COVID-19 Pandemic: Lessons Learnt From a National Referral Hospital in Indonesia.

Abstract

Diabetic foot ulcer (DFU) is one of the most terrifying diabetic complications for patients, due to the high mortality rate and risk for amputation. During the COVID-19 pandemic, many diabetic patients limited their visits to the hospital, resulting in delays for treatment especially in emergency cases. This study aimed to compare the characteristics of patients with DFU pre- and during COVID-19 pandemic period. Methods: This study was a retrospective cohort study using foot registry data. We compared our patients' characteristics pre-COVID-19 pandemic period (1 March 2019-28 February 2020) and during COVID-19 pandemic period (1 March 2020-28 February 2021). Cohorts of 84 and 71 patients with DFU pre- and during COVID-19 pandemic period, respectively, were included in this study. High infection grade (66.7% vs 83.1%, <i>P</i> = .032), osteomyelitis event (72.6% vs 87.3%, <i>P</i> = .04), leukocyte count (15 565.0/μL vs 20 280.0/μL, <i>P</i> = .002), neutrophil-to-lymphocyte ratio (7.7 vs 12.1, <i>P</i> = .008), waiting time-to-surgery (39.0 h vs 78.5 h, <i>P</i> = .034), and number of major amputation (20.2% vs 39.4%, <i>P</i> = .014) were significantly higher during the COVID-19 pandemic period. During the COVID-19 pandemic, patients with DFU had more severe infection, higher proportion of osteomyelitis, longer waiting time for getting surgical intervention, and higher incidence of major amputation.