Neoadjuvant clinical trials provide a window of opportunity for cancer drug discovery.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 35347282.
- Also identified by DOI 10.1038/s41591-022-01681-x and PMC identifier 9901535.
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Abstract
Window-of-opportunity trials, during which patients receive short-duration pre-surgical therapies, provide a platform for understanding the therapies’ mechanisms of action, but will require a paradigm shift in trial design, specimen collection and analysis.
Medical subject headings
- Antineoplastic Agents
- Neoplasms