High Asymptomatic Carriage With the Omicron Variant in South Africa.

Garrett, Nigel; Tapley, Asa; Andriesen, Jessica; Seocharan, Ishen; Fisher, Leigh H; Bunts, Lisa; Espy, Nicole; Wallis, Carole L et al. · Clin Infect Dis · 2022

cross_sectional · Level IV

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Abstract

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

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