Elevated Pre-operative D-Dimer Levels Do Not Impact the Effect of Tranexamic Acid on Revision Total Knee Arthroplasty.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 35365258.
- Also identified by DOI 10.1016/j.ocl.2021.12.001.
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Abstract
The purpose of this study was to determine if elevated pre-operative D-dimer levels in patients undergoing revision total knee arthroplasty (rTKA) pose an increased risk of: (1) post-operative venous thromboemboli (VTE); (2) intra-operative blood loss; and (3) need for transfusion of blood products. Eighty-nine patients who underwent rTKA by a single surgeon between January 1, 2017, and December 31, 2019, met the inclusion criteria. Elevated pre-operative D-dimer levels did not pose an increased risk of VTE, blood loss, or transfusion of blood products, demonstrating that elevated pre-operative D-dimer is not a contraindication to the use of tranexamic acid for rTKA.
Medical subject headings
- Antifibrinolytic Agents
- Arthroplasty, Replacement, Knee
- Tranexamic Acid
Anatomy
- knee