Stem cell-derived β cells go in monkeys.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35395185.
- Also identified by DOI 10.1016/j.stem.2022.03.010.
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Abstract
Du et al. transplanted β cells derived from pluripotent stem cells in diabetic monkeys for the first time, as an intermediate stage toward clinical translation. They observed benefits unfolding over months but also observed immune rejection of the grafts by 5-6 months.
Medical subject headings
- Induced Pluripotent Stem Cells
- Insulin-Secreting Cells
- Pluripotent Stem Cells