Response to Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis".

Terreros-Roncal, J; Moreno-Jiménez, E P; Flor-García, M; Rodríguez-Moreno, C B; Trinchero, M F; Márquez-Valadez, B; Cafini, F; Rábano, A et al. · Science · 2022

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Abstract

Alvarez-Buylla and colleagues provide an alternative interpretation of some of the data included in our manuscript and question whether well-validated markers of adult hippocampal neurogenesis (AHN) are related to this phenomenon in our study. In Terreros-Roncal <i>et al</i>., reconstruction of the main stages of human AHN revealed its enhanced vulnerability to neurodegeneration. Here, we clarify ambiguities raised by these authors.

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