Imaging Aldosterone-Producing Adrenocortical Carcinoma With 68 Ga-Pentixafor PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 35426842.
- Also identified by DOI 10.1097/RLU.0000000000004202.
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Abstract
Chemokine receptor 4 (CXCR4) is a 7-transmembrane G protein-coupled receptor, and pentixafor is considered to be a potent ligand for the CXCR4 receptor. Recently, 68 Ga-pentixafor has been reported as a potential PET imaging agent for CXCR4-positive tumors and inflammatory lesions, including adrenocortical lesions. We report a case of primary aldosteronism due to adrenocortical carcinoma with intense 68 Ga-pentixafor activity on PET/CT.
Medical subject headings
- Adrenal Cortex Neoplasms
- Adrenocortical Carcinoma
- Coordination Complexes