Neither tamoxifen nor aromatase inhibitors increase the risk of Parkinson disease in the UK Biobank cohort.

Lehrer, Steven; Rheinstein, Peter H · Cancer · 2022

prospective_cohort · Level II

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Abstract

Treatment with aromatase inhibitors (AIs) or tamoxifen does not increase the risk of Parkinson’s Disease (PD) in women with breast cancer. The insignificant increase in PD associated with AIs on univariate analysis is an age effect, that is, older women are more likely to receive AIs and more likely to develop PD.

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