Acute Necrotizing Encephalopathy Associated with Coronavirus Disease 2019 in an Infant.

Khan, Mariha; Bhattarai, Samhita; Boyce, Thomas G; Hayek, Reyaad A; Zhadanov, Sergey I; Hooper, Elisabeth E; Fernandez, Edward G; Koehn, Monica A · J Pediatr · 2022

case_report · Level V

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Abstract

A 5-week-old infant born at term was diagnosed with acute necrotizing encephalopathy associated with severe acute respiratory syndrome coronavirus 2 as evidenced by clinical presentation, neuroimaging, and cerebrospinal fluid studies. Our patient was treated with high-dose intravenous methylprednisolone, tocilizumab, and intravenous immunoglobulin with significant short-term clinical improvement but long-term sequelae.

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