Symptom Association for Gastroesophageal Reflux Disease by pH Monitoring After Peroral Endoscopic Myotomy.

DeWitt, John M; Kessler, William R; Wo, John M; Stainko, Sarah; Perkins, Anthony; Dickason, Destenee; Al-Haddad, Mohammad A; Siwiec, Robert · Am J Gastroenterol · 2022

case_series · Level IV

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Abstract

There are limited data correlating symptoms with reflux episodes during pH studies after peroral endoscopic myotomy. Consecutive patients who underwent POEM followed up ≥6 months later by 48-hour ambulatory wireless pH testing off antisecretory therapy were identified. Reflux symptom association was defined as symptom association probability >95%. The most frequent symptoms of heartburn (47.2%), cough (45.1%), and chest pain (39.6%) were associated with a positive reflux symptom association (symptom association probability >95%) in 20.9%, 17.1%, and 19.4%, respectively. There is poor correlation between reported symptoms and esophageal acid exposure during pH testing after POEM.

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