T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy.

Garaud, Soizic; Dieu-Nosjean, Marie-Caroline; Willard-Gallo, Karen · Nat Commun · 2022

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Abstract

Tumor-infiltrating lymphocytes (TILs) are critical in the elimination of cancer cells, a concept highlighted by recent advances in cancer immunotherapy. Significant evidence reveals that their organization in tertiary lymphoid structures together with specific subpopulation composition/balances stimulates cellular crosstalk and anti-tumor immunity in patients.

Medical subject headings