Count on us: T cells in SARS-CoV-2 infection and vaccination.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 35474748.
- Also identified by DOI 10.1016/j.xcrm.2022.100562 and PMC identifier 8872824.
- Licence recorded as CC BY-NC-ND.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Robust T cell responses have been associated with milder outcomes in many infections. T cells also establish long-term memory pools and, as they are predominantly directed toward epitopes encompassing conserved peptides, can respond to SARS-CoV-2 variants, including Omicron. Here, we discuss epitope-specific CD8<sup>+</sup> and CD4<sup>+</sup> T cell responses toward SARS-CoV-2 infection and vaccination, their subsequent persistence into long-term memory, and ongoing work to determine their role in limiting disease severity.
Medical subject headings
- COVID-19
- SARS-CoV-2