Double Trouble: Whole-Genome Doubling Distinguishes Early from Late Ovarian Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 35476137.
- Also identified by DOI 10.1158/1078-0432.CCR-22-0336 and PMC identifier 9306310.
- Licence recorded as CC BY-NC-ND.
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Abstract
Dramatic differences in outcome between early- and late-stage high-grade serous ovarian cancer (HGSC) suggest perhaps distinct genetic origins due to differences in exposures to mutational processes. Evidence to support this hypothesis was recently reported by comparative analysis of copy-number signatures between early- and late-stage HGSCs. See related article by Cheng et al., p. 2911.
Medical subject headings
- Cystadenocarcinoma, Serous
- Fallopian Tube Neoplasms
- Ovarian Neoplasms