Freedom of expression: A synthetic route to metabolites.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35487188.
- Also identified by DOI 10.1016/j.cell.2022.04.007.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Microbial specialized metabolites play key roles in microbiome interactions, but their biosynthetic pathways are difficult to characterize. In this issue, Patel et al. (2022) describe new technologies for the computer-aided redesign of gene clusters to facilitate heterologous expression across diverse hosts and showcase their utility by identifying a new class of microbiome-derived nucleotide metabolites.
Medical subject headings
- Biosynthetic Pathways
- Host Microbial Interactions
- Microbiota