FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35492877.
- Also identified by DOI 10.1016/j.xcrm.2022.100578 and PMC identifier 9040172.
- Licence recorded as CC BY-NC-ND.
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Abstract
FGF21 is a liver-derived hormone primarily involved in glucose/lipid metabolism. A recent study by Flippo and colleagues<sup>1</sup> demonstrates that administration of FGF21 or an FGF21 analog suppresses alcohol consumption in rodents and non-human primates, likely through an amygdalo-striatal circuit.
Medical subject headings
- Alcoholism