Resolving dyskinesias at sustained anti-OCD efficacy by steering of DBS away from the anteromedial STN to the mesencephalic ventral tegmentum - case report.
case_report · Level V
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- Record sourced from PubMed, PMID 35499574.
- Also identified by DOI 10.1007/s00701-022-05206-w and PMC identifier 9427876.
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Abstract
Here we describe therapeutic results in a female patient who underwent bilateral slMFB DBS for OCD. During a 35-month long course of stimulation, she suffered from stimulation-induced dyskinesia of her right leg which we interpreted as co-stimulation of the adjacent anteromedial subthalamic nucleus (amSTN). After reprogramming to steer the stimulation away from the amSTN medial into the direction of the mesencephalic ventral tegmentum (MVT which contains the ventral tegmental area, VTA), the dyskinesias disappeared. Remarkably, anti-OCD efficacy in the presented patient was preserved and achieved with a bilateral stimulation which by our imaging study fully avoided the amSTN.
Medical subject headings
- Deep Brain Stimulation
- Dyskinesias
- Obsessive-Compulsive Disorder
- Subthalamic Nucleus