Krebs takes a turn at cell differentiation.
Level V
Where this comes from
- Record sourced from PubMed, PMID 35508108.
- Also identified by DOI 10.1016/j.cmet.2022.04.005.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In a recent issue of Nature, Arnold et al. report that the partitioning of citrate away from the oxidative steps of the tricarboxylic acid cycle and into the citrate-malate shuttle is essential for mouse embryonic stem cell differentiation. Their findings highlight a crucial role for metabolic regulation in developmental biology.
Medical subject headings
- Citrates
- Citric Acid Cycle