RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies.

Segura, Joan; Rose, Yana; Bittrich, Sebastian; Burley, Stephen K; Duarte, Jose M · Bioinformatics · 2022

basic_science · Level V

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Abstract

Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level. We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies. https://github.com/rcsb/rcsb-saguaro-3d. Supplementary data are available at Bioinformatics online.

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