Spectral homogeneity of human platelets investigated by SERS.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35544536.
- Also identified by DOI 10.1371/journal.pone.0265247 and PMC identifier 9094501.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
This paper describes a detailed study of the spectral homogeneity of human platelets using Surface-enhanced Raman spectroscopy (SERS). We used a combined approach based on multivariate methods as principal component analysis and pair correlation algorithms to investigate platelets spectral properties. The correlation coefficients for each sample have been calculated, and the average coefficient of determination has been estimated. The high degree of spectral homogeneity inside one probe and between them has been revealed. The prospects of obtained results usage for pathologies based on platelet conformations during cardiovascular diseases have been demonstrated.
Medical subject headings
- Blood Platelets
- Spectrum Analysis, Raman