kc-hits: a tool to aid in the evaluation and classification of chemical carcinogens.

Reisfeld, Brad; de Conti, Aline; El Ghissassi, Fatiha; Benbrahim-Tallaa, Lamia; Gwinn, William; Grosse, Yann; Schubauer-Berigan, Mary · Bioinformatics · 2022

other · Level V

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Abstract

The evaluation of chemicals for their carcinogenic hazard requires the analysis of a wide range of data and the characterization of these results relative to the key characteristics of carcinogens. The workflow used historically requires many manual steps that are labor-intensive and can introduce errors, bias and inconsistencies. The automation of parts of the evaluation workflow using the kc-hits software has led to significant improvements in process efficiency, as well as more consistent and comprehensive results. https://gitlab.com/i1650/kc-hits.git. Supplementary data are available at Bioinformatics online.

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