Light controlled signaling initiated by subretinal semiconducting-polymer layer in developing-blind-retina mimics the response of the neonatal retina.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35561667.
- Also identified by DOI 10.1088/1741-2552/ac6f80.
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Abstract
Optoelectronic semiconducting polymer material interfaced with a blind-developing chick-retina (E13-E18) in subretinal configuration reveals a response to full-field flash stimulus that resembles an elicited response from natural photoreceptors in a neonatal chick retina. The response manifests as evoked-firing of action potentials and was recorded using a multi-electrode array in contact with the retinal ganglion layer. Characteristics of increasing features in the signal unfold during different retina-development stages and highlight the emerging network mediated pathways typically present in the vision process of the artificial photoreceptor interfaced retina.
Medical subject headings
- Polymers
- Retina