Clinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017.

Lamberink, Herm J; Vinkers, Christiaan H; Lancee, Michelle; Damen, Johanna A A; Bouter, Lex M; Otte, Willem M; Tijdink, Joeri K · JAMA Intern Med · 2022

cross_sectional · Level IV

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Abstract

This cross-sectional study evaluates the existence and timing of trial registration for randomized clinical trials (RCTs) published from 2002 to 2017 as well as substantive changes to the primary outcomes entered into registry information after those studies started.

Medical subject headings