Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.

Davidson, Shawn M; Schmidt, Daniel R; Heyman, Julia E; O'Brien, James P; Liu, Amy C; Israelsen, William J; Dayton, Talya L; Sehgal, Raghav et al. · Cancer Res · 2022

basic_science · Level V

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Abstract

Differential expression of PKM1 and PKM2 impacts prostate tumorigenesis and suggests a potential therapeutic vulnerability in prostate cancer.

Medical subject headings