Quantification and targeting of elusive neurotoxic amyloid oligomers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35584632.
- Also identified by DOI 10.1016/j.xcrm.2022.100636 and PMC identifier 9133436.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A study by Kass et al.<sup>1</sup> aims to understand the size distribution of amyloid β oligomers in postmortem brain tissues from individuals with Alzheimer's disease (AD) and AD mouse models. Moreover, they show a dose-dependent oligomer elimination by the RD2 compound.
Medical subject headings
- Alzheimer Disease
- Amyloid beta-Peptides