Gene therapy for female infertility: A farfetched dream or reality?

Pathak, Subhajit; Sarangi, Pratiksha; Jayandharan, Giridhara R · Cell Rep Med · 2022

basic_science · Level V

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Abstract

A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al.<sup>1</sup> demonstrate the potential of gene delivery with adeno-associated virus that can cross the blood-follicle barrier and restore oogenesis in congenitally infertile mice.

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