Enhanced Liver Fibrosis Score Stratifies Hepatocellular Carcinoma Risk in Patients With Hepatitis B Surface Antigen Seroclearance.

Mak, Lung-Yi; Cheung, Ka-Shing; Hui, Rex Wan-Hin; Wong, Danny Ka-Ho; Fung, James; Yuen, Man-Fung; Seto, Wai-Kay · Clin Infect Dis · 2022

prospective_cohort · Level II

Where this comes from

Abstract

In this prospective study involving 337 chronic hepatitis B patients who achieved spontaneous hepatitis B surface antigen (HBsAg) seroclearance (SC), serum enhanced liver fibrosis (ELF) before SC was associated with hepatocellular carcinoma (HCC) (hazard ratio 2.588), and ELF <10.8 was associated with >97% reduction in risk of HCC development in patients with age SC ≥ 50 (n = 190).

Medical subject headings