Antibiotic prophylaxis in orthopedic surgery; has the time to reconsider the current practice arrived?
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 35601208.
- Also identified by DOI 10.1016/j.jor.2022.05.008 and PMC identifier 9117254.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The current practice of antibiotic prophylaxis in orthopedic surgery has existed almost 50 years yet little changes have been made. The incidence of methicillin resistant <i>Staphylococci</i> and multi-drug resistant Gram-negative bacteria is growing. We studied the positive cultures after primary hip and knee joint replacement and trauma surgery at our department. Our investigation substantiates the current reports of an increase in oxacillin resistance of <i>Staphylococci</i> and an increase in incidence of Gram-negative bacteria. <i><b>Conclusions</b></i> <b>:</b> The standard use of cephalosporins for prophylaxis does not provide the necessary protection that it used to. We suggest that the recommendations and practice of antibiotic prophylaxis should be reconsidered. Level III - retrospective cohort study.