Cumulative Mycobacterium tuberculosis Infection Incidence (Measured Primarily by Tuberculin Skin Test) Among Infants With Human Immunodeficiency Virus Exposure: Observational Follow-up of an Isoniazid Prophylaxis Trial.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35607710.
- Also identified by DOI 10.1093/cid/ciac393 and PMC identifier 10200296.
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Abstract
Cumulative 24-month Mycobacterium tuberculosis infection incidence (measured primarily by tuberculin skin test [TST]) was high among human immunodeficiency virus exposed but uninfected infants (8.7 [95% confidence interval, 6.3-11.9] per 100 person-years). Trend for decreased TST positivity among infants at trial end (12 months postenrollment) randomized to isoniazid at 6 weeks of age was not sustained through observational follow-up to 24 months of age. NCT02613169.
Medical subject headings
- Tuberculosis
- HIV Infections
- Mycobacterium tuberculosis