Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Neutralization After Antenatal Messenger RNA Vaccination.

Rottenstreich, Amihai; Vorontsov, Olesya; Alfi, Or; Zarbiv, Gila; Oiknine-Djian, Esther; Zigron, Roy; Kleinstern, Geffen; Mandelboim, Michal et al. · Clin Infect Dis · 2022

prospective_cohort · Level II

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Abstract

We evaluated the neutralization efficiency against SARS-CoV-2 Omicron variant in maternal and cord blood sera after antenatal BNT162b2 vaccination. Neutralizing antibodies against Omicron were lacking at the time of delivery after 2-dose vaccination. A third booster dose was essential in building neutralizing antibody capacity against Omicron among mothers and neonates.

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