The case for increasing diversity in tissue-based functional genomics datasets to understand human disease susceptibility.
Where this comes from
- Record sourced from PubMed, PMID 35614099.
- Also identified by DOI 10.1038/s41467-022-30650-8 and PMC identifier 9133089.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Tissue-based functional genomics resources including molecular quantitative trait loci datasets lack diversity in ancestry and tissue types and thus are inadequate for comprehensively investigating gene regulation. Global efforts to increase the tissue diversity will help achieve more equitable medical care.
Medical subject headings
- Genetic Variation
- Genomics