Doravirine Concentrations and Human Immunodeficiency Virus Type 1 RNA in the Genital Fluids of Virologically Suppressed Adults Switching to Doravirine Plus Emtricitabine/Tenofovir Alafenamide.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35616112.
- Also identified by DOI 10.1093/cid/ciac410 and PMC identifier 13017405.
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Abstract
Doravirine (DOR) concentrations and HIV-1 RNA were evaluated in genital fluids from adults with HIV on stable therapy who switched to DOR + FTC/TAF. High protein-unbound DOR concentrations were observed in both seminal plasma and cervicovaginal fluid. DOR + FTC/TAF maintained viral suppression in genital fluids in all but 1 participant.
Medical subject headings
- HIV-1
- Anti-HIV Agents
- HIV Infections