Flip-flop genomics: Charting inversions in the human population.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35623326.
- Also identified by DOI 10.1016/j.cell.2022.05.002.
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Abstract
Detecting large genomic inversions has long been challenging. In a new study, Porubsky et al. resolve these complex rearrangements in 41 individuals and discover wide regions that undergo recurrent inversions, some of which even toggle back and forth (Porubsky et al., 2022). Many of these regions are associated with genomic disorders.
Medical subject headings
- Gene Rearrangement
- Genomics