In patients with COVID-19 receiving IMV or ECMO, adding baricitinib to usual care reduced all-cause mortality.

Shah, Aditya; O'Horo, John C · Ann Intern Med · 2022

rct · Level II

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Abstract

Ely EW, Ramanan AV, Kartman CE, et al. <b>Efficacy and safety of baricitinib plus standard of care for the treatment of critically ill hospitalised adults with COVID-19 on invasive mechanical ventilation or extracorporeal membrane oxygenation: an exploratory, randomised, placebo-controlled trial.</b> Lancet Respir Med. 2022;10:327-36. 35123660.

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