OverProt: secondary structure consensus for protein families.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35674374.
- Also identified by DOI 10.1093/bioinformatics/btac384.
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Abstract
Every protein family has a set of characteristic secondary structures. However, due to individual variations, a single structure is not enough to represent the whole family. OverProt can create a secondary structure consensus, showing the general fold of the family as well as its variation. Our server provides precomputed results for all CATH superfamilies and user-defined computations, visualized by an interactive viewer, which shows the secondary structure element type, length, frequency of occurrence, spatial variability and β-connectivity. OverProt Server is freely available at https://overprot.ncbr.muni.cz. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software
- Proteins