Mutation and tissue lineage lead to organ-specific cancer.
Where this comes from
- Record sourced from PubMed, PMID 35676353.
- Also identified by DOI 10.1038/d41586-022-01535-z and PMC identifier PMC5936048.
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Abstract
Cancer-promoting mutations tend to result in tumours arising only in certain organs, but the reasons for this specificity are not fully understood. The analysis of human kidney cancer provides clues to solving this mystery.