Multisystem Inflammatory Syndrome in Children During Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta and Omicron Variant Circulation-United States, July 2021-January 2022.

Miller, Allison D; Yousaf, Anna R; Bornstein, Ethan; Wu, Michael J; Lindsey, Katherine; Melgar, Michael; Oster, Matthew E; Zambrano, Laura D et al. · Clin Infect Dis · 2022

case_series · Level IV

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Abstract

We describe 2116 multisystem inflammatory syndrome in children (MIS-C) cases reported to the Centers for Disease Control and Prevention during Delta and Omicron circulation from July 2021 through January 2022. Half of MIS-C patients were aged 5-11 years, 52% received intensive care unit-level care, and 1.1% died. Only 3.0% of eligible patients were fully vaccinated prior to MIS-C onset.

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