Broad Antimicrobial Resistance in a Case of Relapsing Babesiosis Successfully Treated With Tafenoquine.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 35684960.
- Also identified by DOI 10.1093/cid/ciac473.
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Abstract
We describe a case of relapsing babesiosis in an immunocompromised patient. A point mutation in the Babesia microti 23S rRNA gene predicted resistance to azithromycin and clindamycin, whereas an amino acid change in the parasite cytochrome b predicted resistance to atovaquone. Following initiation of tafenoquine, symptoms and parasitemia resolved.
Medical subject headings
- Babesiosis
- Aminoquinolines