Continued Increase of Erythromycin Nonsusceptibility and Clindamycin Nonsusceptibility Among Invasive Group A Streptococci Driven by Genomic Clusters, United States, 2018-2019.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 35684991.
- Also identified by DOI 10.1093/cid/ciac468 and PMC identifier 11120049.
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Abstract
We analyzed 9630 invasive GAS surveillance isolates in the USA. From 2015-2017 to 2018-2019, significant increases in erythromycin-nonsusceptibility (18% vs 25%) and clindamycin-nonsusceptibility (17% vs 24%) occurred, driven by rapid expansions of genomic subclones. Prevention and control of clustered infections appear key to containing antimicrobial resistance.
Medical subject headings
- Clindamycin
- Streptococcal Infections