Transcriptional Analysis for Tuberculosis in Pregnant Women From the PRegnancy Associated Changes In Tuberculosis Immunology (PRACHITi) Study.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35686302.
- Also identified by DOI 10.1093/cid/ciac437 and PMC identifier 9761891.
- Licence recorded as CC BY-NC-ND.
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Abstract
A new tuberculosis (TB) diagnostic cartridge assay, which detects a 3-gene TB signature in whole blood, was not diagnostic in women with maternal TB disease in India (area under the curve [AUC] = 0.72). In a cohort of pregnant women, we identified a novel gene set for TB diagnosis (AUC = 0.97) and one for TB progression (AUC = 0.96).
Medical subject headings
- Tuberculosis
- Pregnancy Complications, Parasitic
- Mycobacterium tuberculosis