Management of a Patient With Metastatic Gastrointestinal Neuroendocrine Tumor and Meningioma Submitted to Peptide Receptor Radionuclide Therapy With 177 Lu-DOTATATE.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 35695716.
- Also identified by DOI 10.1097/RLU.0000000000004307.
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Abstract
A 76-year-old woman affected by pancreatic neuroendocrine tumor previously subjected to surgery with progressive liver disease and a concomitant mild symptomatic meningioma of the left pontocerebellar angle underwent 4 cycles of peptide receptor radionuclide therapy with 177 Lu-DOTATATE. A prophylactic therapy with corticosteroids was carried out before each treatment cycle, and the neurosurgery unit was alerted in case of cerebral edema and related neurologic symptoms. A 68 Ga-DOTATOC PET/CT scan performed after the completion of the 4 cycles' treatment documented a hepatic partial response and a substantial stability of the brain mass. No neurological complications occurred during treatment and follow-up.
Medical subject headings
- Intestinal Neoplasms
- Meningeal Neoplasms
- Meningioma
- Neuroendocrine Tumors
- Organometallic Compounds
- Pancreatic Neoplasms